The maximum amount of DLPA that is safe is unknown. However, consistent toxicity in healthy people has not been reported with 1,500 mg per day or less of DLPA, except for occasional nausea, heartburn, or transient headaches.
When 100 mg of LPA per 2.2 pounds body weight or more was given to animals, a variety of complex problems occurred, leading two researchers to have concerns about potential toxicity of high amounts in humans.39 While these concerns were directed at LPA specifically, they are likely to be equally applicable to DLPA. Although no serious adverse effects have been reported in humans taking phenylalanine, amounts greater than 1,500 mg per day should be supervised by a doctor.
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