Calcium D-glucarate is the calcium salt of
D-glucaric acid, a natural substance found in many fruits and vegetables.
Where is it found?
Calcium D-glucarate is available in capsules and tablets. Foods high in glucaric acid (a
form of calcium D-glucarate) include apples,
Brussels sprouts, broccoli,
cabbage, and bean sprouts.1
Calcium D-glucarate has
been used in connection with the following conditions (refer to the
individual health concern for complete information):
Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit.
Who is likely to be deficient?
Calcium D-glucarate is not an essential nutrient, and thus no deficiency state exists.
How much is usually taken?
Manufacturers of calcium D-glucarate recommend a daily intake of 200 to 400 mg.
Are there any side effects or interactions?
No side effects have been reported with calcium D-glucarate. Although there are no known
drug interactions, many drugs (especially hormones) are metabolized in the liver by binding to
glucuronic acid. It is therefore possible that taking calcium D-glucarate could increase the
elimination of certain drugs or hormones from the body, thereby reducing their effectiveness.
If you are taking any prescription medication, please consult your physician or pharmacist
before taking calcium D-glucarate.
At the time of writing, there were no well-known drug interactions
with calcium D-glucarate.
References (To view, roll mouse over the "References" heading; to hide, click on the heading)
1. Dwivedi C, Heck WJ, Downie AA, et al. Effect of calcium glucarate on
beta-glucuronidase activity and glucarate content of certain vegetables and fruits.
Biochem Med Metab Biol 1990;43:83–92.
The information presented in Healthnotes is for informational purposes
only. It is based on scientific studies (human, animal, or in vitro), clinical
experience, or traditional usage as cited in each article. The results reported may not
necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over the counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. Information expires September 2008.
Reliable
and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit.
