Lipase is an enzyme that is used by the
body to break down dietary fats into an
absorbable form.
Where is it found?
Most of the body’s lipase is manufactured in the pancreas, although some of it is
secreted in the saliva, as well. Pancreatin contains lipase along with two other groups of enzymes: proteases and amylase.
Lipase has been used in
connection with the following conditions (refer to the individual
health concern for complete information):
Reliable
and relatively consistent scientific data showing a substantial health benefit. Contradictory, insufficient, or preliminary studies
suggesting a health benefit or minimal health benefit. For an herb, supported by traditional use but minimal
or no scientific evidence. For a supplement, little scientific support and/or minimal health
benefit.
Products that contain lipase also usually contain other enzymes that help digest carbohydrates and protein. In
the U.S., pancreatin, which contains lipase, amylase, and proteases, is rated against a
government standard. For example, “9X pancreatin” is nine times stronger than the
government standard. Each “X” contains 25 USP units of amylase, 2 USP units of
lipase, and 25 USP units of proteolytic enzymes. Taking 1.5 grams of 9X pancreatin (or a
higher amount at lower potencies) with each meal can help people with pancreatic insufficiency
digest food.
Are there any side effects or interactions?
Lipase does not generally cause any side effects at the amounts listed above.
At the time of writing, there were no well-known drug interactions
with lipase.
References (To view, roll mouse over the "References" heading; to hide, click on the heading)
1. Patel RS, Johlin FC Jr, Murray JA. Celiac disease and recurrent
pancreatitis. Gastrointest Endosc 1999;50:823–7.
2. Hegnhoj J, Hansen CP, Rannem T, et al. Pancreatic function in
Crohn’s disease. Gut 1990;31:1076–9.
3. Suarez F, Levitt MD, Adshead J, Barkin JS. Pancreatic supplements
reduce symptomatic response of healthy subjects to a high fat meal. Dig Dis Sci
1999;44:1317–21.
The information presented in Healthnotes is for informational purposes
only. It is based on scientific studies (human, animal, or in vitro), clinical
experience, or traditional usage as cited in each article. The results reported may not
necessarily occur in all individuals. For many of the conditions discussed, treatment with
prescription or over the counter medication is also available. Consult your doctor,
practitioner, and/or pharmacist for any health problem and before using any supplements or
before making any changes in prescribed medications. Information expires September 2008.
